Update on Lipodystrophy in HIV

" Individual when they first come into the clinic the most obvious thing would be that they would have lost so that -- don't -- Many people receiving treatment HIV experience one or more symptoms of a condition commonly called like -- to her. If you examine people early on they had lost -- on their arm and their legs and he seemed very well kinda not holes because again that is not covering them. Other symptoms include the accumulation of fat in the abdomen. High levels of cholesterol. And insulin resistance which can lead to diabetes. In fact there are so many aspects of what people have been calling like -- dystrophy a recent trend among doctors is to focus on individual components."

" One thing has emerged over the last year has been the recognition. That and there isn't a single. Syndrome. So -- food -- what is -- dystrophy. The federal water moves things that you recognized -- That problem."

" Another recent development among doctors who treat HIV. Is a recognition and there is no simple cause of -- go to. A few years ago there had been consensus now shown to be wrong. -- drug in the class known as protease inhibitors were almost exclusively responsible for the problem."

" None of record parents Prodi is in her letters started to deduced. So Robertson kiss and then there was an assumption. That it is evident in all the problems. Almost forgotten is that the prisoners weren't you on their own."

" Doctors still believes some protein inhibitors are associated with our -- Buddhist or symptoms specifically elevated cholesterol. Insulin resistant and the accumulation of -- Research now shows that other drug known nucleus side -- transcript ace inhibitors may contribute to the loss of that. But mostly the research points away from generalizations. I think -- finding out is that rather than protease contenders cause one tell us that he nuclear analysts cut another it turns out that probably. Are more suspect fat -- and more specific ground attack. That various drugs within the same may not -- same kinds of toxicity as one ongoing research project called the HIV out and study. -- Has helped doctors better understand factors associated with higher risk of developing -- We find that there are we call host factors that are associated with -- disease factors that are associated -- and drug sectors that are associated with that one at -- recently released data focus is on to law also called. Like -- atrophy. The most actors from the data are those relating to the patient routed and the disease or treatment. The older people are likely they are developed like -- at. He always a factor another running the associated factors would be a race car came in seemed to have higher rates of Michael atropine the upstate oh oh draw a strong link between like the accuracy and how sick a patient was before recovering -- treatment. This measured by a little mark for counselor CD four cells in the blood. These are immune systems. That are targeted and ruling -- How long ditch are being in action since being important and Howard on -- infection. -- in other words. -- How about things from garments in -- projector -- Carl. We like to be an individual who's going through. To our. -- The hopes that he somewhat controversially. Also found no significant ties between any drug and that we -- post -- these factors were statistically significant. At a stronger association. What happened with rifle either under the ground and their for the drugs. We're not as important as disease host factory. Those data do not -- square with others study. And doctors believe -- drugs or at least partially responsible was like Buddhist retreat including federal. A recent -- scale research study showed that -- one drug believed to cause that loss was replaced by another. Patient regained about 33%. Of those that they had lost."

" Many of us were very concerned that this might not do -- and try to convince people who are probably on the market is a broker. In the studies. Shows that concern there can be some recovered. And I and drizzle possible she found when its car and from the right return to their -- never really came full blown out."

" Another small recent study showed a small -- ability to outlaw when patients with Michael district who experienced in Denver and we're given a drug which he used to treat diabetes. Doctors are also reporting good results in treating like Buddhist retreat with changes in diet exercise. Testosterone. Growth hormone and drugs that lower cholesterol. Researchers greatly expanding our understanding of the complex syndrome known as like -- dystrophy. And doctors are hopeful they will develop effective strategies. To help better treat like -- Esther well still helping patients like HIV affect."