IBD and Colorectal Cancer: Keeping a Close Watch

" People with inflammatory bowel disease at increased risk of developing colorectal cancer compared to the general population. But doctors caution the risk must be kept in perspective. Barbara remains a rare application of this disease. But these studies have estimated the light on prevalence of this conditioner that overall about three point 6% three and a half percent or three people hundred in their life and night about the condition. We can break it down further we actually ask what's the likely over time because I'm significant charitable. 2%. After -- year -- inclination. Each and after. Twenty years and disease and 8%. Hurting your. Opening with altered it's like he's increased risk. -- some people with crohn's disease. Wasn't appreciated until the 1980. That patients with crohn's disease -- an increased risk as well. Because lacrosse -- don't necessarily have to use in the colon it turns out that probably. Patience with crime -- in the global unrest are developing colon cancer patients with all glad provided that they have a similar direction to yeah. And -- into -- ball. Within a population of people IB DD or other risk factor. There it can't turn and about his scenes include more extensive disease -- other -- more improbably and well. Longer terrain and to -- People who have a family history of colon cancer Independent sort of driven product or about is -- cancer where there I'd -- And I can to him with us in -- of the bile ducts in the liver called primary or in college -- appears to be an Independent risk factor a inflammatory to. More recently we are or are suggesting that the degree of and me and is an Independent actor. Colonoscopy and biopsy of tissue samples taken from the colon bargaining technique used in -- colon cancer. Or or precancerous conditions. The sequence of events that lead to cancer and inflammatory bowel disease are not the same as -- and people who don't have inflammatory bowel disease. -- we believed to occur is that in May -- in. A pre date called display. Display is not necessarily visible to the caller. And so the war the way we look at this by doing random surveillance -- throughout the bowel. And they had -- followed carefully analyzed those for display. When the pathologist returns a report of Malaysia. Many doctors recommend having to colon removed regardless of how early or advance or the cellular changed."

" If an expert pathologist tells -- high -- displeasure. Does it. Very strong likelihood that they may already be cancer in the colon at bats aren't they were in the near future the likelihood maybe anywhere from 45 to 65 for and and in several studies. So -- great pleasure now. Most position would recommend that the -- come -- because of higher risk of either he coincidental hold it at that time or subsequent colon cancer. We slowly displaced it has a little bit more controversy. He Corzine rate of simultaneous Culkin or or a clinical cancer can be a little bit lower. But nonetheless. Because of our failings or inability. Who see all cancers before they become problematic. Many doctors will recommend even with a low grade -- later that you consider removing the colon."

" When dealing with -- great to play. Or -- inflammation makes it difficult to determine whether to present. Some doctors may recommend tightened surveillance in lieu of immediate surgery. Yeah alternatives -- two point low -- to Malaysia and even the position of the Haitian."

" Doesn't want an operation would be just very close monitoring meaning bringing the patient back for another realist or -- can. I like to stay within three to six months if you're very nervous there's nothing wrong with bringing them back in a month or two months depending on the level of anxiety. But you don't want to wait much more than about a month because -- latest confirmed or god forbid if they -- great displeasure or worse. You want to be able to act on that quickly. While people with IBT face higher risk of colorectal cancer drug that they routinely take may help reduce that risk. Chemo prevention is that you you live on medication. Could not part. To prevent the development in this case -- so when we talk about you know prevention. For colorectal cancer and all sort of -- we're talking about medications used for the prevention of displacement --"

" One drug -- equally -- it also known as dot has shown some promise in helping protect again colon cancer and split. In people with IBD and primaries roasting -- giant of the liver. Drugs used for a loan may have a similar effect. The other major therapy that we an -- and seems to have you prevent property. Is the five amino -- a look at therapies which many occasions on dollars there mr. Allen mean drugs such as you call. And -- is all and died and to. That plastic -- over many years now has an insult to. Any one of those drugs may have to do not chemo preventive properties. Doctors say any possible -- prevent it is likely to take place early on in the person's cellular changed."

" The drugs that we have thought that we -- you know prevent NHL it's not clear where in the collider. To Malaysia to cancer pathway that they work. Certainly preliminary evidence suggests that in the earlier days prior to the development of displeasure. And that you get to Malaysia beat the horse is already out of the barn. Another development in cancer prevention for people with IBD. Is an improvement in technique to examine the colon I think there's some new developments that are coming on the -- applicable at the time of Europe -- colonoscopy. The doctor and their own you know record -- where ability and inject a little blue dog that will highlight areas that might not have been visible to the NATO ally. And target are out in those areas that we have a better chance of picking up displeasure if it's there -- that's a very promising technique. In the future continued surveillance may become more common following could go free Asia especially. In the prevention. -- active. But now doctors say displays -- call to action. If I agreed to -- Asia is identified. Walk. Don't have a run of walked over with her and I'll do yourself -- favor. And happier or are you may impact at the -- already. And while it would be nice to -- the call and it's far more important to him. The patients -- low grade to place. I would recommend this and you can probably talk a little bit lower. But you should certainly need a search and you can certainly discuss with you again in Toronto. Just how much you might eat at ran her happening at that moment that are already. -- developing cancer in the future."